Gallbladder Cancer

About Gallbladder Cancer

Gallbladder cancer is a rare cancer that arises from the gallbladder. Only 2 per 100,000 people develop this type of cancer in the USA yearly.

Gallstones and chronic inflammation are the most common risk factors identified. Gallbladder cancer can spread by direct invasion into the liver, as well as by lymphatic and hematogenous spread. Even early stage gallbladder cancers can spread via the lymphatic system.

First level nodal spread are classified as N-1 or cyst and pericholeodochal lymph nodes. N-2 nodes include peripancreatic and celiac nodes. Spread to interaortocaval nodes are classified as M-1.


Surgical Treatment of Gallbladder Cancer

The majority of gallbladder cancers are adenocarcinoma, or cancers that begin in glandular cells. Surgical resection to include segment 4b and 5 of the liver, in combination with a portal lymph node dissection, is the treatment of choice for cancers confined to the gallbladder.

Excision of the common bile duct is reserved for cases where the cystic duct stump is positive for cancer cells. Regional or portal lympadenectomy is included. A negative cystic duct margin is required as a part of gallbladder cancer surgeries.


Choosing Your Surgeon

With over 20 years of highly-specialized experience and training, Dr. Mark Fraiman is recognized as an expert in the treatment of gallbladder cancer in Baltimore.

Using a multidisciplinary approach, Dr. Fraiman works closely with a team of specialists at St. Joseph Medical Center’s Liver and Pancreas Center to come up with an individualized plan for each of our gallbladder patients.

Dr. Fraiman’s commitment to exceptional patient care is reflected in the numerous honors and awards he has received throughout his medical career.


Symptoms of Gallbladder Cancer

  • Abdominal pain
  • Jaundice
  • Weight loss
  • Anemia

Staging of Gallbladder Cancer

  • Tis Carcinoma insitu
  • T1a Tumor invades lamina propria
  • T1b Tumor invades muscle layer
  • T2 Tumor invades perimuscular connective tissue
  • T 3 Tumor invades liver
  • T 4 Tumor involves portal vein or hepatic artery
In the following video, Dr. Mark Fraiman discusses the diagnosis and treatment of gallbladder cancer in Baltimore, MD.